Sled Dog Society of Wales
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Picture
 B12 Deficiency or Cobalamin Malabsorption
 
Cobalamin malabsorption is the genetic abnormality by which the vitamin B12, also known as cobalamin, is not able to be absorbed by the intestine.  This condition often occurs secondary to the nonexistence of a specific binding receptor in the lower intestine (the ileum) for essential factor-cobalamin complex (IF-cbl).  This is an uncommon disease that tends to affect certain breeds of dogs that are predisposed to it such as the Giant Schnauzer, Beagles and Boarder Collies; however other breeds of dogs can inherit or develop this condition.  For example in the case of the Giant Schnauzer, it is inherited as a simple autosomal recessive trait.  (Autosmal - DNA is a term used in genetic genealogy to describe DNA which is inherited from the autosomalchromosomes).
 
Symptoms and Types
  • Anorexia
  • Lethargy
  • Failure to gain weight
 
Causes
The cause of this disease is often through genetic inheritancee; however it can develop due to another underlying disease or injury.  However, there are generally certain breeds that seem to be at risk for this disease.
 
Diagnosis
Your veterinarian will perform a complete physical exam on your dog, with full blood panel, including a chemical blood profile, a complete blood count, and a urinalysis.  The blood serum will be examined for cobalamin concentration levels; low levels would be suggestive of an absorption malfunction.  The serum check will also give suggest that there may be a secondary condition that is affecting the body by how high the levels of white blood cells are in the blood serum.  Urinalysis may also suggest a higher than normal level of white blood cells also.  You will need to supply your vet with a thorough history of your dog’s health leading up to the onset of symptoms, including any hereditary information you may have discovered from your dogs breeder.
 
Your veterinarian may discover chronic non-regenerative anaemia, where the dog’s body doesn’t respond to the deficiency of red blood cells, or moderate to severe neutropenia, where the dog’s body is suffering from an abnormal low amount of white blood cells.
 
Further diagnostic tests may also reveal the failure of cobalamin to absorb is related to other congenital metabolic diseases, or a parasite in the gastrointestinal tract.
 
Treatment
This can easily be on an outpatient basis, with long-term supplementary administration of cobalamin such as tablets or oral liquids.  Any other medications such as B12 injections will be as performed by your veterinarian on a regular basis; this depends on the test results.

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  • SDSW THERAPY DOGS HOME
    • NEW VOLUNTEERS >
      • NEW VOLUNTEERS PAPERWORK
    • ESTABLISHMENTS >
      • HOSPITAL REGISTRATION FORMS
      • SCHOOL REGISTRATION FORMS
      • CARE HOME REGISTRATION FORMS
      • OTHER BUSINESS REGISTRATION FORMS
    • CORPORATE PARTNERS
    • REGISTERED VOLUNTEERS >
      • VOLUNTEERS SDSWTD Merchandise
  • About
    • Club Ethos
    • Club Code of Ethics
    • Club Photos
    • Club Membership
    • Club Merchandise >
      • Pyrography
      • Car Decals
      • Clothing
      • Custom Embroidery Designs
      • Dog Accessories
      • Miscellaneous
    • Meet the Pack & Club Event Photos
    • Rainbow Bridge
  • Education & Public Speaking
  • Contact
  • Ain't Nothing But A Hound Day
    • Gleblands Park - Newport
    • Victoria Park - Cardiff
    • Romilly Park - Barry
    • Roath Recreation Ground - Cardiff
  • Club Sponsors 2024
  • Canine Care - First Aid & Health & Wellbeing
    • Canine First Aid Kit Contents
    • CANINE CARE >
      • Anal Glands/Sacks
      • Burns
      • Coconut Oil
      • Dental Care
      • Dry Dog Food
      • Grooming and maintenance
      • Heat Stroke
      • How To Trim Your Dogs Claws
      • Nutrition
      • Raw Feeding
      • Spaying & Neutering
      • Toxic Food - Fruits, vegtables & Fish
      • Turmeric Powder
      • Vaccinations, Worming, Microchipping >
        • HOMEOPATHIC VACCINES - NOSODES & TITRE TESTING
        • Kennel Cough
        • Microchipping
        • Worming, Flea & Tick Prevention & Parasites
        • Vaccinaions
      • Veterinary Clinical Examination
      • Vitaimin E
      • Zinc Deficency
    • Bandaging & Wound Cleaning
    • Emergency First Aid A-Z >
      • Abscesses
      • Adder Snake Bite
      • Bee Stings & Insect Bites
      • Bleeding (external)
      • Bleeding (internal)
      • Bloat
      • Chemical Burns
      • Choking
      • CPR - Cardio Pulmonary Resusitation
      • Dehydration
      • Dental Emergencies
      • Difficult Births
      • Drowning
      • Eye Injuries
      • Electrocution
      • Fainting - "Syncope"
      • False Widow Spider Bite
      • Fever
      • Fox Bites
      • Fractures
      • Heatstroke
      • Hot Spots - Canine Acute Moist Dermatitis
      • Hypothermia
      • Nose Bleed
      • Paralysis
      • Poisoning and Exposure to Toxins
      • Penetrating Injuries
      • Rat Bites
      • Seizures
      • Shock
      • Straining & Constipation
      • Transporting Injurerd Dogs
  • Health & Wellbeing
    • Abnormal Heart Rhythm in Dogs
    • Alaskan Husky Encephalopathy (Sub acute Necrotizing Encephalomyelopathy)
    • B12 Deficiency or Cobalamin Malabsorption
    • Breathing Difficulties
    • Canine Athletes Heart Syndrome
    • Congenital Heart Disease in Dogs
    • Epilepsy
    • Hip dysplasia
    • Hypoglycemia
    • Hypothyroidism & Hyperthyroidism
    • Joint Luxation
    • Ligament and Tendon Tears
    • Metabolic Myopathy
    • Paw Pad Problems
    • Portal Systemic Shunts
    • Pyometra & Cystic Endometrial Hyperplasia
    • Snow Nose
    • Stomach Ulcers
    • Tendonitis
    • Urinary Tract Health
    • Infectious diseases >
      • Alabama Rot
      • Cryptococcosis
      • Distemper
      • Erlichiosis
      • Hepatitis
      • Histoplasmosis
      • Parvovirus
      • Rabies
  • Controlling Your Dog In Public
    • Banned Breeds
    • Dangerous Dog Act 2017
    • Dog fouling
    • Public Spaces Protection Orders
    • XL Bully Law 2024
  • Donation & Fundraising
    • Easy Fundraising
  • Evolution Of Dogs
    • Breeds >
      • Alaskan Husky
      • Aalaskan Klee Kai
      • Alaskan Malamute
      • Chow Chow
      • Crossd Breed - Huskamute
      • Greenland Dogs
      • Japanese Akita Inu & American Akita
      • Samoyed
      • Siberian Husky
      • Tamaskan
      • Czechoslovakian wolf dog
      • Saarlooswolfhond
      • Timberwolfdog
  • Equipment
    • Collars
    • Cooling Coats & Mats
    • Scooters, Dry Land Rig and Sleds
    • Walking Belt
    • Dog Weather Shelter
    • Head Collar
    • Leads
    • Harnesses
    • Stake out lines
  • Puppy and dog walking tips
  • Training
    • Agility Training
    • Canicross
    • Crate Training
    • FLYBALL TRAINING
    • Heelwork to Music Training
    • Obedience training >
      • Bite Inhibition
      • Leave it Training
      • Recall Training
      • Sit Training
      • Sit & Stay Training
      • Walking to Heel Training
      • Working In Racing Harness Sled/Dry Land Rig or Scooter
    • RING CRAFT TRAINING
    • Scent Training
    • Temperature Guide to Safely Work Your Dog
    • Toilet Training
    • Vocal Commands
    • Weight Pull Training